WASHINGTON, D.C. (July 30, 2013) – America’s biopharmaceutical research companies are developing 444 new medicines to prevent and treat neurological disorders, according to a new report released today by the Pharmaceutical Research and Manufacturers of America (PhRMA).Continue reading
Author Archive: AZBio
UNIVERSITY PRESIDENTS URGE THE PRESIDENT AND CONGRESS: CLOSE THE INNOVATION DEFICIT
Dear President Obama & Members of the 113th Congress:
Our nation’s role as the world’s innovation leader is in serious jeopardy. The combination of eroding federal investments in research and higher education, additional cuts due to sequestration, and the enormous resources other nations are pouring into these areas is creating a new kind of deficit for the United States: an innovation deficit. Closing this innovation deficit—the widening gap between needed and actual investments—must be a national imperative.
Ignoring the innovation deficit will have serious consequences: a less prepared, less highly skilled U.S. workforce, fewer U.S.-based scientific and technological breakthroughs, fewer U.S.-based patents, and fewer U.S. start-ups, products, and jobs. These impacts may not be immediately obvious because the education and research that lead to advances do not happen overnight. But the consequences are inevitable if we do not reverse course.
The path for resolving appropriations, the debt limit, and a potential long-term budget agreement this fall is unclear. What should be clear is that the answer to our nation’s fiscal woes must include sustained strategic federal investments in research and student financial aid to close the innovation deficit and bolster our nation’s economic and national security for decades to come.
More than half of U.S. economic growth since World War II is a consequence of technological innovation, overwhelmingly resulting from federally-funded scientific research. Such groundbreaking research has led to life-saving vaccines, lasers, MRI, touchscreens, GPS, the Internet, and many other advances that have improved lives and generated entire new sectors of our economy. Many of the university researchers making those discoveries would not have the opportunity to be in their labs were it not for federal support of research and higher education.
Having witnessed this nation’s success at turning investments in research and higher education into innovation and economic growth, countries such as China, Singapore, and Korea have dramatically increased their own investments in these areas. Over the past decade these other nations’ investments have climbed at two to four times the rate of U.S. research and development expenditures. It is equally troubling that the U.S. has fallen to 16th among developed countries in the share of young adults who hold college degrees. Our nation is rapidly losing ground, and further cuts including sequestration will only exacerbate the problem.
Because the innovation deficit undermines economic growth it harms our nation’s overall fiscal health, worsening long-term budget deficits and debt. Investments in research and education are not inconsistent with long-term deficit reduction; they are vital to it.
Throughout our history, this nation has kept the promise of a better tomorrow to each generation. This has been possible because of our economic prosperity based in large part on America’s role as global innovation leader. Failing to deal with the innovation deficit will pass to future generations the burdens of lost leadership in innovation, economic decline, and limited job opportunities.
We call upon you to reject unsound budget cuts and recommit to strong and sustained investments in research and education. Only then can we ensure that our nation’s promise of a better tomorrow endures.
Sincerely,
Hunter R. Rawlings III, Association of American Universities
Peter McPherson, Association of Public and Land-grant Universities
Kenneth E. Peacock, Appalachian State University
Michael Crow, Arizona State University
Jay Gogue, Auburn University
Harvey G. Stenger, Binghamton University, The State University of New York
Robert W. Kustra, Boise State University
Robert A. Brown, Boston University
Mary Ellen Mazey, Bowling Green State University
Frederick M. Lawrence, Brandeis University
Christina H. Paxson, Brown University
Edward Stolper, California Institute of Technology
Jeffrey D. Armstrong, California Polytechnic State University, San Luis Obispo
J. Michael Ortiz, California State Polytechnic University, Pomona
Timothy P. White, California State University
Richard R. Rush, California State University Channel Islands
Paul J. Zingg, California State University, Chico
Willie J. Hagan, California State University, Dominguez Hills
Leroy M. Morishita, California State University, East Bay
John D. Welty, California State University, Fresno
Mildred García, California State University, Fullerton
Donald J. Para, California State University, Long Beach
James M. Rosser, California State University, Los Angeles
Dianne F. Harrison, California State University, Northridge
Alexander Gonzalez, California State University, Sacramento
Tomás D. Morales, California State University, San Bernardino
Karen S. Haynes, California State University San Marcos
Subra Suresh, Carnegie Mellon University
Barbara R. Snyder, Case Western Reserve University
Lisa S. Coico, The City College of New York
William Kelly, The City University of New York
James F. Barker, Clemson University
Ronald M. Berkman, Cleveland State University
Anthony A. Frank, Colorado State University
Michael V. Martin, Colorado State University System
Lee C. Bollinger, Columbia University
Mortimer H. Neufville, Coppin State University
David J. Skorton, Cornell University
Harry L. Williams, Delaware State University
Richard H. Brodhead, Duke University
Steven Ballard, East Carolina University
James W. Wagner, Emory University
Mark B. Rosenberg, Florida International University
Eric Barron, Florida State University
G.P. “Bud” Peterson, Georgia Institute of Technology
Drew Gilpin Faust, Harvard University
Michael A. McRobbie, Indiana University
Charles R. Bantz, Indiana University-Purdue University Indianapolis
Steven Leath, Iowa State University
Ronald J. Daniels, Johns Hopkins University
Kirk H. Schulz, Kansas State University
Lester A. Lefton, Kent State University
Mary Evans Sias, Kentucky State University
L. Rafael Reif, Massachusetts Institute of Technology
David Hodge, Miami University
Lou Anna K. Simon, Michigan State University
Glenn D. Mroz, Michigan Technological University
Mark E. Keenum, Mississippi State University
Cheryl B. Schrader, Missouri University of Science and Technology
Waded Cruzado, Montana State University
Susan A. Cole, Montclair State University
Joel S. Bloom, New Jersey Institute of Technology
Garrey Carruthers, New Mexico State University
John Sexton, New York University
William Woodson, North Carolina State University
Dean L. Bresciani, North Dakota State University
John D. Haeger, Northern Arizona University
Douglas D. Baker, Northern Illinois University
Betty J. Youngblood, Oakland University
Joseph A. Alutto, The Ohio State University
Roderick J. McDavis, Ohio University
Edward J. Ray, Oregon State University
Rodney A. Erickson, The Pennsylvania State University
Wim Wiewel, Portland State University
Christopher L. Eisgruber, Princeton University
David Leebron, Rice University
Robert L. Barchi, Rutgers, The State University of New Jersey
Elliot Hirshman, San Diego State University
Leslie E. Wong, San Francisco State University
Ruben Arminana, Sonoma State University
David L. Chicoine, South Dakota State University
Rita Cheng, Southern Illinois University Carbondale
Glenn Poshard, Southern Illinois University System
Nancy L. Zimpher, The State University of New York
Samuel L. Stanley, Jr., Stony Brook University, State University of New York
Neil D. Theobald, Temple University
R. Bowen Loftin, Texas A&M University
M. Duane Nellis, Texas Tech University
Scott S. Cowen, Tulane University
Gilbert Rochon, Tuskegee University
Robert J. Jones, University at Albany SUNY
Luis Proenza, The University of Akron
Robert E. Witt, The University of Alabama System
Tom Case, University of Alaska Anchorage
Brian Rogers, University of Alaska Fairbanks
John R. Pugh, University of Alaska Southeast
Patrick Gamble, University of Alaska System
Ann Weaver Hart, The University of Arizona
G. David Gearhart, University of Arkansas
Laurence B. Alexander, University of Arkansas at Pine Bluff
Donald R. Bobbitt, University of Arkansas System
Satish K. Tripathi, University at Buffalo, The State University of New York
Mark G. Yudof, University of California
Nicholas B. Dirks, University of California, Berkeley
Linda P.B. Katehi, University of California, Davis
Michael V. Drake, University of California, Irvine
Gene Block, University of California, Los Angeles
Dorothy Leland, University of California, Merced
Jane Close Conoley, University of California, Riverside
Pradeep Khosla, University of California, San Diego
Susan Desmond-Hellmann, University of California, San Francisco
Henry T. Yang, University of California, Santa Barbara
George Blumenthal, University of California, Santa Cruz
John C. Hitt, University of Central Florida
Santa J. Ono, University of Cincinnati
Donald M. Elliman, Jr., University of Colorado Denver | Anschutz Medical Campus
Philip P. DiStefano, University of Colorado Boulder
Patrick T. Harker, University of Delaware
James E. Lyons, Sr., University of the District of Columbia
Bernie Machen, University of Florida
Jere W. Morehead, The University of Georgia
MRC Greenwood, University of Hawaii System
Tom Apple, University of Hawaii at Manoa
Renu Khator, University of Houston
Robert A. Easter, University of Illinois
Paula Allen-Meares, University of Illinois at Chicago
Phyllis M. Wise, University of Illinois at Urbana-Champaign
Sally Mason, The University of Iowa
Bernadette Gray-Little, The University of Kansas
Eli Capilouto, University of Kentucky
Paul W. Ferguson, The University of Maine
Wallace D. Loh, University of Maryland
William E. Kirwan, University System of Maryland
Robert L. Caret, University of Massachusetts
Kumble R. Subbaswamy, University of Massachusetts Amherst
Mary Sue Coleman, University of Michigan
Eric W. Kaler, University of Minnesota
Lendley C. Black, University of Minnesota Duluth
Brady J. Deaton, University of Missouri
Tim M. Wolfe, University of Missouri System
Leo E. Morton, University of Missouri-Kansas City
Thomas F. George, University of Missouri-St. Louis
Royce C. Engstrom, University of Montana
James B. Milliken, University of Nebraska
Neal J. Smatresk, University of Nevada, Las Vegas
Marc A. Johnson, University of Nevada, Reno
Mark W. Huddleston, University of New Hampshire
Robert G. Frank, The University of New Mexico
Carol L. Folt, The University of North Carolina at Chapel Hill
Philip L. Dubois, University of North Carolina at Charlotte
Linda P. Brady, University of North Carolina at Greensboro
Gary L. Miller, University of North Carolina at Wilmington
Thomas W. Ross, The University of North Carolina System
V. Lane Rawlins, University of North Texas
V. Burns Hargis, Oklahoma State University
Michael R. Gottfredson, University of Oregon
Amy Gutmann, University of Pennsylvania
Mark A. Nordenberg, University of Pittsburgh
David M Dooley, University of Rhode Island
Joel Seligman, University of Rochester
Harris Pastides, University of South Carolina
James W. Abbott, University of South Dakota
Judy Genshaft, University of South Florida
C. L. Max Nikias, University of Southern California
Joe DiPietro, The University of Tennessee
Jimmy G. Cheek, University of Tennessee, Knoxville
Vistasp M. Karbhari, University of Texas at Arlington
William Powers, Jr., University of Texas at Austin
David E. Daniel, University of Texas at Dallas
Diana Natalicio, University of Texas at El Paso
Francisco Cigarroa, The University of Texas System
Lloyd A. Jacobs, The University of Toledo
E. Thomas Sullivan, The University of Vermont
Teresa A. Sullivan, University of Virginia
Michael K. Young, University of Washington
Kevin P. Reilly, University of Wisconsin System
Rebecca Blank, University of Wisconsin-Madison
Michael Lovell, University of Wisconsin-Milwaukee
Bob Sternberg, University of Wyoming
Stan L. Albrecht, Utah State University
Nicholas S. Zeppos, Vanderbilt University
Michael Rao, Virginia Commonwealth University
Charles W. Steger, Virginia Tech
Elson S. Floyd, Washington State University
Mark S. Wrighton, Washington University in St. Louis
Allan Gilmour, Wayne State University
James P. Clements, West Virginia University
John M. Dunn, Western Michigan University
Peter Salovey, Yale University
Raymond L. Woosley, M.D., Ph.D. appointed to ARCA biopharma Board of Directors
Broomfield, CO, July 30, 2013 – ARCA biopharma, Inc. (Nasdaq: ABIO), a biopharmaceutical company developing genetically-targeted therapies for cardiovascular diseases, today announced that Raymond L. Woosley, M.D., Ph.D, has been appointed to the Company’s Board of Directors. He will serve on the Compensation and Nominating and Corporate Governance Committees of the Board of Directors.
Dr. Woosley is currently the President, Emeritus, of the Critical Path Institute (C-Path), a non-profit, public-private partnership with the United States Food and Drug Administration, of which he was a founder, and where he served as President, Chief Executive Officer and Chairman of the Board from 2005 to 2011. Since 2012, Dr. Woosley is also the President and Chairman of the Board of the Arizona Center for Education and Research on Therapeutics (AzCERT), an independent, nonprofit research and education organization dedicated to the safe use of medicines.
“We are honored to have Dr. Woosley join the ARCA Board of Directors,” said Dr. Michael R. Bristow, President and Chief Executive Officer of ARCA. “With his extensive expertise and decades-long experience in cardiovascular clinical pharmacology, anti-arrhythmic therapeutics, pharmacogenetic drug development and regulatory science, Dr. Woosley will be a valuable addition to the ARCA Board as we continue the development of Gencaro.”
“I am delighted to join the Board of an organization focused on advancing cardiovascular science and potentially improved medical therapeutics,” said Dr. Woosley. “ARCA’s personalized medicine approach and its comparative effectiveness clinical trial of Gencaro incorporate important aspects of what I believe will be more efficient, informative and effective drug development in the future.”
Since 2001, Dr. Woosley has also been a Professor of Medicine and Pharmacology at The University of Arizona Health Sciences Center, and Professor, Emeritus, since 2012, where he was also Vice President for Health Sciences from 2001 to 2005, and Dean of the College of Medicine from 2001 to 2002. From 1988 to 2000, Dr. Woosley was a professor of pharmacology and medicine at the Georgetown University School of Medicine, where he was also Director of the Institute of Cardiovascular Sciences from 1994 to 2000, and Division Chief, Clinical Pharmacology, in the Department of Medicine from 1988 to 1994. Dr. Woosley earned his Ph.D. in Pharmacology from the University of Louisville, and his M.D. from the University of Miami.
Dr. Woosley is a former member of the National Academy of Science’s Institute of Medicine’s Drug Forum, and his research has been published in over 265 peer-reviewed publications and 50 book chapters.
ARCA also announced that Jean-Francois Formela, M.D., Partner at Atlas Ventures, resigned from the ARCA Board of Directors. Dr. Formela has been a member of ARCA’s Board of Directors since February 2006.
“We thank Jean-Francois for his leadership and service over the past seven years as a Director for ARCA,” said Dr. Bristow. “His experience and insight into the pharmaceutical industry have served the company well and directly contributed to the Company reaching its current state, approaching the launch of GENETIC-AF, our Phase 2B/3 clinic trial of Gencaro.”
About ARCA biopharma
ARCA biopharma is dedicated to developing genetically-targeted therapies for cardiovascular diseases. The Company’s lead product candidate, GencaroTM (bucindolol hydrochloride), is an investigational, pharmacologically unique beta-blocker and mild vasodilator being developed for atrial fibrillation. ARCA has identified common genetic variations that it believes predict individual patient response to Gencaro, giving it the potential to be the first genetically-targeted atrial fibrillation prevention treatment. ARCA has a collaboration with Medtronic, Inc. for support of the Phase 2B portion of the GENETIC-AF trial. For more information please visit www.arcabiopharma.com.
Safe Harbor Statement
This press release contains “forward-looking statements” for purposes of the safe harbor provided by the Private Securities Litigation Reform Act of 1995. These statements include, but are not limited to, statements regarding the potential impact of ARCA’s personalized medicine approach to drug development and the comparative effectiveness GENETIC-AF trial, the potential for genetic variations to predict individual patient response to Gencaro, Gencaro’s potential to treat atrial fibrillation, future treatment options for patients with atrial fibrillation, and the potential for Gencaro to be the first genetically-targeted atrial fibrillation prevention treatment. Such statements are based on management’s current expectations and involve risks and uncertainties. Actual results and performance could differ materially from those projected in the forward-looking statements as a result of many factors, including, without limitation, the risks and uncertainties associated with: the Company’s financial resources and whether they will be sufficient to meet the Company’s business objectives and operational requirements; results of earlier clinical trials may not be confirmed in future trials, the protection and market exclusivity provided by the Company’s intellectual property; risks related to the drug discovery and the regulatory approval process; and, the impact of competitive products and technological changes. These and other factors are identified and described in more detail in ARCA’s filings with the SEC, including without limitation the Company’s annual report on Form 10-K for the year ended December 31, 2012, and subsequent filings. The Company disclaims any intent or obligation to update these forward-looking statements.
Contact:
Derek Cole
Investor Relations Advisory Solutions
720.940.2163, derek.cole@arcabiopharma.com
###
Knowledge In Numbers: Pairing Digital Pathology with Integrated Biostatistics
Rapid changes in the pharmaceutical industry and in the discipline of pathology expand the need for biostatisticsContinue reading
Learning from a Virus: Keeping Genes Under Wraps
By studying how a virus that infects most people at some point in their lives packages its genetic material during infection, an international collaboration of researchers has made discoveries that help scientists better understand virus-host interactions and may open new avenues for therapies.Continue reading
TGen2School gets big boost from APS Foundation
$20,000 APS Foundation grant helps fund TGen2School education initiativeContinue reading
How Strong Is Arizona’s Health-Care Safety Net?
Center for Rural Health to Study Arizona’s Health-Care Safety Net System Under the Affordable Care Act. Continue reading
TGen experience helps Helios Scholars prepare for future
Focused scientific internship helps build Arizona’s biomedical workforceContinue reading
Putting the Brakes on Inflammation
Researchers have uncovered a signal that prevents the immune system from spinning out of control. The findings could help develop more effective therapies for autoimmune disorders, allergies, chronic inflammation and cancer.Continue reading
Without fair payment, biomedical innovation cannot make it the last mile.
Biomedical innovations in the area of molecular diagnostics are the framework for a new golden age of medicine. Unfortunately, a hurdle on the path from discovery to development to delivery could block these life sustaining and life saving innovations from getting to the patient.Continue reading